2-Bromo-4-(((tert-butyldimethylsilyl)oxy)methyl)thiazole
≥95%
Reagent
Code: #150503
CAS Number
936691-31-5
blur_circular Chemical Specifications
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Molecular Information
Weight
308.31 g/mol
Formula
C₁₀H₁₈BrNOSSi
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Registry Numbers
MDL Number
MFCD26399018
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Storage & Handling
Storage
2-8°C, dry, sealed
description Product Description
Used as an intermediate in the synthesis of biologically active compounds, particularly in pharmaceutical and agrochemical research. Its structure allows for selective functionalization, making it valuable in constructing complex molecules. The bromo group enables cross-coupling reactions, such as Suzuki or Heck reactions, while the silyl-protected hydroxymethyl group can be deprotected to introduce polar functionality. Commonly employed in the development of kinase inhibitors and antifungal agents. Also utilized in solid-phase synthesis and combinatorial chemistry due to its stability and reactivity profile.
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