4-Chloromethyl-2-Methylthiazole Hydrochloride
98%
Reagent
Code: #160895
CAS Number
77470-53-2
blur_circular Chemical Specifications
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Molecular Information
Weight
184.09 g/mol
Formula
C₅H₇Cl₂NS
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Registry Numbers
MDL Number
MFCD00067725
thermostat
Physical Properties
Melting Point
161-163 °C
Boiling Point
217.5°C
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Storage & Handling
Storage
-20°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antihypertensive drugs and angiotensin II receptor antagonists. It plays an important role in forming carbon-heteroatom bonds due to the reactivity of the chloromethyl group, making it valuable in constructing heterocyclic compounds. Commonly employed in medicinal chemistry for derivatization of thiazole-based bioactive molecules. Also utilized in agrochemicals for the production of certain fungicides and plant growth regulators. Its hydrochloride salt form enhances stability and solubility in polar solvents, facilitating its use in various synthetic routes.
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