Silica gel plates are widely used in thin-layer chromatography (TLC) for the separation and analysis of chemical compounds. They serve as a stationary phase, allowing the separation of mixtures based on their polarity and interaction with the silica gel surface. This application is essential in laboratories for identifying and purifying substances, such as pharmaceuticals, natural products, and organic compounds. In the pharmaceutical industry, silica gel plates are used to ensure the purity and consistency of drugs by analyzing raw materials and finished products. In research, they help in studying reaction progress, isolating compounds, and characterizing unknown substances. Additionally, they are employed in forensic science to detect and analyze trace evidence, such as drugs or toxins. Silica gel plates are also used in environmental testing to identify pollutants in water, soil, and air samples. Their simplicity, cost-effectiveness, and versatility make them a fundamental tool in analytical chemistry across various fields.