Silica gel plates are widely used in chromatography for separating and analyzing complex mixtures of compounds. In thin-layer chromatography (TLC), they serve as the stationary phase, allowing for the separation of substances based on their polarity and interaction with the silica surface. This application is essential in pharmaceuticals for identifying and purifying drug compounds, in forensic science for analyzing substances like drugs or toxins, and in food safety for detecting contaminants or additives. Additionally, they are used in research laboratories for monitoring chemical reactions and isolating specific compounds from mixtures. Their versatility, ease of use, and cost-effectiveness make them a staple in analytical chemistry.