Hexadecyl sulfide finds its primary application in the field of lubrication and as an additive in industrial oils. Its chemical structure makes it an effective friction modifier, reducing wear and tear on mechanical components by forming a protective layer on metal surfaces. This property is particularly valuable in high-stress environments such as automotive engines and heavy machinery, where it enhances the longevity and efficiency of moving parts.

In addition to its lubricating properties, hexadecyl sulfide is utilized in the synthesis of specialty chemicals, including surfactants and emulsifiers. Its ability to act as a stabilizer in formulations makes it suitable for use in cosmetics, personal care products, and certain pharmaceutical preparations. Furthermore, it serves as an intermediate in organic synthesis, contributing to the production of more complex chemical compounds.

In the field of materials science, hexadecyl sulfide is employed as a surface modifier to improve the compatibility of inorganic materials with organic matrices. This application is particularly relevant in the development of advanced composites and coatings, where it enhances adhesion and performance characteristics. Its versatility and effectiveness in various industrial processes underscore its importance as a functional chemical in multiple sectors.