1,2-Propanedithiol is primarily used in the synthesis of organic compounds, particularly in the preparation of complex molecules in pharmaceutical research. It serves as a key reagent in the formation of thioacetals and thioketals, which are crucial intermediates in various chemical reactions. Additionally, this compound is employed in the modification of proteins and peptides, aiding in the study of their structure and function. Its ability to act as a reducing agent makes it valuable in processes that require the stabilization of sensitive compounds. In material science, 1,2-Propanedithiol is utilized in the development of polymers and coatings, enhancing their durability and performance.