4-(Trifluoromethyl)thiophenol is primarily used as a building block in organic synthesis, particularly in the pharmaceutical and agrochemical industries. Its trifluoromethyl group enhances the biological activity and stability of compounds, making it valuable in the development of drugs and pesticides. It is also employed in the synthesis of ligands for catalysis, especially in cross-coupling reactions, due to its electron-withdrawing properties. Additionally, it serves as a key intermediate in the production of specialty chemicals and materials, such as polymers and coatings, where its unique structure imparts desirable properties like chemical resistance and durability.