2-Bromo-5-(difluoromethyl)thiophene
95%
Reagent
Code: #150608
CAS Number
924646-90-2
blur_circular Chemical Specifications
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Molecular Information
Weight
213.04 g/mol
Formula
C₅H₃BrF₂S
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Registry Numbers
MDL Number
MFCD22378823
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Storage & Handling
Storage
-20°C, avoid light, inert gas storage
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of biologically active compounds. Its structure allows for selective functionalization, making it valuable in building complex molecules in medicinal chemistry. Commonly employed in cross-coupling reactions such as Suzuki or Stille reactions to form carbon-carbon bonds. Also utilized in the preparation of fluorinated analogs of natural products and drug candidates, where the difluoromethyl group enhances metabolic stability and lipophilicity.
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