SPD304 is primarily recognized for its role in inhibiting tumor necrosis factor alpha (TNF-α), a cytokine involved in systemic inflammation. This makes it valuable in research focused on inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis. By blocking TNF-α, SPD304 helps in studying the pathways and mechanisms of these conditions, aiding in the development of potential therapeutic strategies. Additionally, it is utilized in biochemical assays to understand TNF-α signaling and its interaction with other cellular components, contributing to advancements in immunology and drug discovery.