(S)-10-((Dimethylamino)methyl)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl acetate

≥95%

Reagent Code: #238018
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CAS Number 123948-88-9

science Other reagents with same CAS 123948-88-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 463.48 g/mol
Formula C₂₅H₂₅N₃O₆
badge Registry Numbers
MDL Number MFCD00884565
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used in research as a derivative of camptothecin, this compound functions as a topoisomerase I inhibitor, making it valuable in anticancer drug development. It is studied for its ability to interfere with DNA replication in tumor cells, leading to cell death. Its structure allows for improved solubility and stability compared to parent compounds, which enhances its potential for use in chemotherapy formulations. It has shown activity against various cancer cell lines, particularly in lung, colon, and ovarian cancers. Researchers also explore its use in targeted delivery systems, such as antibody-drug conjugates or nanoparticle-based therapies, to increase specificity and reduce side effects.

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inventory 5mg
10-20 days ฿52,690.00

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(S)-10-((Dimethylamino)methyl)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl acetate
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Used in research as a derivative of camptothecin, this compound functions as a topoisomerase I inhibitor, making it valuable in anticancer drug development. It is studied for its ability to interfere with DNA replication in tumor cells, leading to cell death. Its structure allows for improved solubility and stability compared to parent compounds, which enhances its potential for use in chemotherapy formulations. It has shown activity against various cancer cell lines, particularly in lung, colon, and ovarian cancers. Researchers also explore its use in targeted delivery systems, such as antibody-drug conjugates or nanoparticle-based therapies, to increase specificity and reduce side effects.
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