Used as a reagent in organic synthesis, particularly in trifluoromethylation reactions where introduction of the CF₃ group is required. It serves as a stable and easy-to-handle source of trifluoromethyl anions, enabling the modification of pharmaceuticals, agrochemicals, and functional materials. Its sodium salt form enhances solubility in polar solvents, facilitating its use in aqueous or mixed solvent systems. Commonly applied in the development of fluorinated compounds with improved metabolic stability and bioavailability.