TRPM8 antagonist 14 is primarily used in research focused on understanding the role of TRPM8 channels in various physiological processes. It is applied in studies investigating pain mechanisms, particularly in conditions involving cold hypersensitivity or chronic pain. This compound helps researchers explore the potential of TRPM8 inhibition as a therapeutic strategy for managing pain associated with cold stimuli or neuropathic disorders. Additionally, it is utilized in preclinical models to assess its efficacy in modulating temperature sensation and its impact on related pathways. Its application extends to the development of novel analgesics targeting TRPM8 channels for improved pain management therapies.