SSR128129E free acid is primarily utilized in research settings, particularly in the study of angiogenesis and cancer biology. It functions as a potent inhibitor of fibroblast growth factor receptor (FGFR) signaling, making it a valuable tool for investigating the role of FGFR pathways in tumor growth and vascular development. Researchers employ this compound to explore potential therapeutic strategies for cancers that are driven by FGFR overexpression or mutations. Additionally, it aids in understanding the molecular mechanisms underlying angiogenesis, which is crucial for developing treatments for diseases characterized by abnormal blood vessel formation, such as certain cancers and retinal disorders. Its application extends to preclinical studies where it helps evaluate the efficacy of targeting FGFR signaling in various experimental models.