VEGFR-2-IN-6 is primarily utilized in research settings to study angiogenesis and cancer biology. It functions as a potent inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2), which plays a critical role in the formation of new blood vessels. By blocking this receptor, the compound helps in understanding the mechanisms of tumor growth and metastasis, as many cancers rely on angiogenesis for their progression. Researchers use VEGFR-2-IN-6 to explore potential therapeutic strategies for targeting cancers that are dependent on vascular development. Additionally, it serves as a tool compound in preclinical studies to evaluate the efficacy of anti-angiogenic drugs. Its application extends to investigating conditions like age-related macular degeneration and other diseases where abnormal blood vessel formation is a key factor.