Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its difluoro-methoxy aromatic structure enhances metabolic stability and membrane permeability, making it valuable in optimizing drug candidates for improved bioavailability and target binding. Commonly employed in late-stage functionalization during medicinal chemistry campaigns to introduce fluorinated motifs that modulate lipophilicity and pharmacokinetic profiles.