Ethyl 6-bromo-8-fluoro-4-oxo-1H-quinoline-3-carboxylate
95%
Reagent
Code: #184602
CAS Number
228728-06-1
science Other reagents with same CAS 228728-06-1
blur_circular Chemical Specifications
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Molecular Information
Weight
314.11 g/mol
Formula
C₁₂H₉BrFNO₃
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Registry Numbers
MDL Number
MFCD25572662
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of advanced antimicrobial agents. Its structure allows for further functionalization at the 6 and 8 positions, enabling the creation of compounds with enhanced potency, broader spectrum activity, and improved pharmacokinetic profiles. Commonly employed in pharmaceutical research to build quinolone cores that target DNA gyrase and topoisomerase IV in bacteria. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize antibacterial efficacy and reduce resistance development.
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