Ethyl 6-bromo-8-fluoro-4-oxo-1H-quinoline-3-carboxylate

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Reagent Code: #184602
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CAS Number 228728-06-1

science Other reagents with same CAS 228728-06-1

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Weight 314.11 g/mol
Formula C₁₂H₉BrFNO₃
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MDL Number MFCD25572662
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of advanced antimicrobial agents. Its structure allows for further functionalization at the 6 and 8 positions, enabling the creation of compounds with enhanced potency, broader spectrum activity, and improved pharmacokinetic profiles. Commonly employed in pharmaceutical research to build quinolone cores that target DNA gyrase and topoisomerase IV in bacteria. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize antibacterial efficacy and reduce resistance development.

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inventory 5g
10-20 days ฿38,800.00

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Ethyl 6-bromo-8-fluoro-4-oxo-1H-quinoline-3-carboxylate
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Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of advanced antimicrobial agents. Its structure allows for further functionalization at the 6 and 8 positions, enabling the creation of compounds with enhanced potency, broader spectrum activity, and improved pharmacokinetic profiles. Commonly employed in pharmaceutical research to build quinolone cores that target DNA gyrase and topoisomerase IV in bacteria. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to optimize antibacterial efficacy and reduce resistance development.
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