(E)-4,4,5,5-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-1,3,2-dioxaborolane

95%(stabilized with MEHQ)

Reagent Code: #185712
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CAS Number 642066-70-4

science Other reagents with same CAS 642066-70-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 268.16 g/mol
Formula C₁₄H₂₅BO₄
badge Registry Numbers
MDL Number MFCD03788736
inventory_2 Storage & Handling
Storage -20°C, Sealed, Drying, Inert Gas

description Product Description

Used as a key intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. Its main application lies in the construction of complex organic molecules, including pharmaceuticals and agrochemicals, where it enables the formation of carbon-carbon bonds. The tetrahydropyranyl (THP) protecting group stabilizes sensitive functionalities during reaction sequences, allowing selective transformations. After coupling, the THP group can be easily removed under mild acidic conditions, making this compound valuable in multi-step syntheses requiring precise functional group control. It is especially useful in the preparation of bioactive compounds and conjugated systems in medicinal chemistry and materials science.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿4,230.00
inventory 1g
10-20 days ฿12,000.00
inventory 5g
10-20 days ฿55,990.00
(E)-4,4,5,5-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-1,3,2-dioxaborolane
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Used as a key intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. Its main application lies in the construction of complex organic molecules, including pharmaceuticals and agrochemicals, where it enables the formation of carbon-carbon bonds. The tetrahydropyranyl (THP) protecting group stabilizes sensitive functionalities during reaction sequences, allowing selective transformations. After coupling, the THP group can be easily removed under mild acidic conditions, making this compound valuable in multi-step syntheses requiring precise functional group control. It is especially useful in the preparation of bioactive compounds and conjugated systems in medicinal chemistry and materials science.
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