(E)-4,4,5,5-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-1,3,2-dioxaborolane
95%(stabilized with MEHQ)
Reagent
Code: #185712
CAS Number
642066-70-4
science Other reagents with same CAS 642066-70-4
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Molecular Information
Weight
268.16 g/mol
Formula
C₁₄H₂₅BO₄
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Registry Numbers
MDL Number
MFCD03788736
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Storage & Handling
Storage
-20°C, Sealed, Drying, Inert Gas
description Product Description
Used as a key intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. Its main application lies in the construction of complex organic molecules, including pharmaceuticals and agrochemicals, where it enables the formation of carbon-carbon bonds. The tetrahydropyranyl (THP) protecting group stabilizes sensitive functionalities during reaction sequences, allowing selective transformations. After coupling, the THP group can be easily removed under mild acidic conditions, making this compound valuable in multi-step syntheses requiring precise functional group control. It is especially useful in the preparation of bioactive compounds and conjugated systems in medicinal chemistry and materials science.