(E)-tert-butyl 2-(bromomethyl)-3-fluoroallylcarbamate
98%
Reagent
Code: #186293
CAS Number
1478364-89-4
science Other reagents with same CAS 1478364-89-4
blur_circular Chemical Specifications
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Molecular Information
Weight
268.12 g/mol
Formula
C₉H₁₅BrFNO₂
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Registry Numbers
MDL Number
MFCD30802527
thermostat
Physical Properties
Boiling Point
307.7±42.0 °C(Predicted)
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Storage & Handling
Density
1.330±0.06 g/cm3(Predicted)
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of fluorinated analogs of biologically active molecules. Its allylic bromide functionality enables selective substitution reactions, making it valuable in medicinal chemistry for constructing complex nitrogen-containing structures. The tert-butyl carbamate group acts as a protected amine, allowing stepwise assembly of peptide-like chains or heterocycles. Commonly applied in research settings for designing enzyme inhibitors or receptor modulators where fluorine substitution enhances metabolic stability and binding affinity.