2-Fluorobenzoyl chloride
99%
Reagent
Code: #186459
CAS Number
393-52-2
science Other reagents with same CAS 393-52-2
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
158.56 g/mol
Formula
C₇H₄ClFO
badge
Registry Numbers
MDL Number
MFCD00000656
thermostat
Physical Properties
Melting Point
4 °C(lit.)
Boiling Point
90-92 °C/15 mm Hg(lit.)
inventory_2
Storage & Handling
Density
1.328 g/mL at 25 °C(lit.)
Storage
Room temperature
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It plays a key role in introducing the 2-fluorobenzoyl group into larger molecules, which can enhance metabolic stability and binding affinity in drug candidates. Commonly employed in the preparation of fluorinated analogs of bioactive compounds, especially in the development of anti-inflammatory, antifungal, and central nervous system agents. Also utilized in the manufacture of liquid crystals and specialty polymers due to the unique electronic properties imparted by the fluorine atom. Its reactivity makes it valuable in Friedel-Crafts acylation and other acyl transfer reactions under controlled conditions.