3-Fluorophenylmagnesium bromide solution
1.0M in 2-MeTHF
Reagent
Code: #187003
CAS Number
17318-03-5
science Other reagents with same CAS 17318-03-5
blur_circular Chemical Specifications
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Molecular Information
Weight
199.3 g/mol
Formula
FC₆H₄MgBr
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Registry Numbers
MDL Number
MFCD00672007
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a versatile reagent in organic synthesis, particularly for forming carbon-carbon bonds. It serves as a nucleophile in reactions with carbonyl compounds such as aldehydes, ketones, and esters to produce fluorinated alcohols, which are valuable intermediates in pharmaceutical and agrochemical development. The presence of the fluorine atom enhances metabolic stability and bioavailability in drug molecules, making this reagent useful in the synthesis of fluorinated analogs of biologically active compounds. It is also employed in the preparation of complex aromatic structures through coupling reactions and in the construction of fluorinated building blocks for materials science applications. Handling requires inert atmosphere due to sensitivity to moisture and air.