3-fluoro-4-hydroxyphenylboronic acid
≥95%
Reagent
Code: #187387
CAS Number
182344-14-5
science Other reagents with same CAS 182344-14-5
blur_circular Chemical Specifications
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Molecular Information
Weight
155.92 g/mol
Formula
C₆H₆BFO₃
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Registry Numbers
MDL Number
MFCD06659838
thermostat
Physical Properties
Boiling Point
331.5°C at 760 mmHg
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Storage & Handling
Storage
2-8°C
description Product Description
Used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, to construct biaryl compounds for pharmaceuticals and agrochemicals. Its boronic acid group enables carbon-carbon bond formation under mild conditions. The fluorine and hydroxyl substituents enhance reactivity and direct regioselectivity in coupling reactions. Commonly employed in drug discovery for building fluorinated aromatic scaffolds, which improve metabolic stability and bioavailability in active pharmaceutical ingredients. Also utilized in the development of sensors and functional materials due to its specific binding properties with diols and catecholamines.