5-Fluoro-2-methoxybenzene-1-sulfonylchloride

97%

Reagent Code: #187411
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CAS Number 67475-56-3

science Other reagents with same CAS 67475-56-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 224.64 g/mol
Formula C₇H₆ClFO₃S
badge Registry Numbers
MDL Number MFCD03618459
thermostat Physical Properties
Boiling Point 309.8±27.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.455±0.06 g/cm3(Predicted)
Storage 2-8℃

description Product Description

Used primarily as an intermediate in the synthesis of pharmaceuticals, especially in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine atom enhances metabolic stability and bioavailability. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester linkages commonly found in bioactive molecules. It is also employed in agrochemical synthesis to build herbicides and fungicides, leveraging the electron-withdrawing fluoro and sulfone groups to fine-tune compound reactivity and target specificity. Additionally, it serves as a building block in materials science for creating specialty polymers with improved thermal and oxidative resistance.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿970.00
inventory 25g
10-20 days ฿3,780.00
inventory 100g
10-20 days ฿13,050.00
5-Fluoro-2-methoxybenzene-1-sulfonylchloride
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Used primarily as an intermediate in the synthesis of pharmaceuticals, especially in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine atom enhances metabolic stability and bioavailability. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester linkages commonly found in bioactive molecules. It is also employed in agrochemical synthesis to build herbicides and fungicides, leveraging the electron-withdrawing fluoro and sulfone groups to fine-tune compound reactivity and target specificity. Additionally, it serves as a building block in materials science for creating specialty polymers with improved thermal and oxidative resistance.
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