5-Fluoro-2-methoxybenzene-1-sulfonylchloride
97%
Reagent
Code: #187411
CAS Number
67475-56-3
science Other reagents with same CAS 67475-56-3
blur_circular Chemical Specifications
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Molecular Information
Weight
224.64 g/mol
Formula
C₇H₆ClFO₃S
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Registry Numbers
MDL Number
MFCD03618459
thermostat
Physical Properties
Boiling Point
309.8±27.0 °C(Predicted)
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Storage & Handling
Density
1.455±0.06 g/cm3(Predicted)
Storage
2-8℃
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceuticals, especially in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluorine atom enhances metabolic stability and bioavailability. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester linkages commonly found in bioactive molecules. It is also employed in agrochemical synthesis to build herbicides and fungicides, leveraging the electron-withdrawing fluoro and sulfone groups to fine-tune compound reactivity and target specificity. Additionally, it serves as a building block in materials science for creating specialty polymers with improved thermal and oxidative resistance.