5-Fluoro-2-(trifluoromethyl)benzoic Acid
98%
Reagent
Code: #187485
CAS Number
654-99-9
science Other reagents with same CAS 654-99-9
blur_circular Chemical Specifications
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Molecular Information
Weight
208.11 g/mol
Formula
C₈H₄F₄O₂
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Registry Numbers
MDL Number
MFCD00083521
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Physical Properties
Melting Point
80-83°C (Lit.)
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of anti-inflammatory and central nervous system drugs. Its structure allows for enhanced metabolic stability and bioavailability in drug molecules. Commonly employed in the preparation of selective serotonin reuptake inhibitors (SSRIs) and other bioactive compounds where fluorine substitution improves potency. Also utilized in agrochemicals for the production of herbicides and fungicides due to its electron-withdrawing properties and resistance to degradation. Serves as a building block in medicinal chemistry for structure-activity relationship (SAR) studies involving aromatic carboxylic acids.