5-Fluoro-2-(trifluoromethyl)benzoyl Chloride

97%

Reagent Code: #187501
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CAS Number 216144-70-6

science Other reagents with same CAS 216144-70-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 226.55 g/mol
Formula C₈H₃ClF₄O
badge Registry Numbers
MDL Number MFCD00083534
thermostat Physical Properties
Boiling Point 169°C (Lit.)
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry

description Product Description

Used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals, this compound plays a key role in introducing fluorinated benzoyl groups into larger molecules. Its high reactivity makes it valuable in the preparation of herbicides and fungicides, where the fluorine atoms enhance biological activity and stability. It is also employed in the development of active pharmaceutical ingredients, particularly in drugs targeting central nervous system disorders and inflammation. Due to the presence of both fluorine and trifluoromethyl groups, it contributes to improved metabolic resistance and membrane permeability in drug candidates. Commonly used in carbonyl coupling reactions, it reacts with amines and alcohols to form amides and esters, respectively, which are essential structural motifs in many bioactive compounds.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿3,950.00
5-Fluoro-2-(trifluoromethyl)benzoyl Chloride
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Used primarily as an intermediate in the synthesis of pharmaceuticals and agrochemicals, this compound plays a key role in introducing fluorinated benzoyl groups into larger molecules. Its high reactivity makes it valuable in the preparation of herbicides and fungicides, where the fluorine atoms enhance biological activity and stability. It is also employed in the development of active pharmaceutical ingredients, particularly in drugs targeting central nervous system disorders and inflammation. Due to the presence of both fluorine and trifluoromethyl groups, it contributes to improved metabolic resistance and membrane permeability in drug candidates. Commonly used in carbonyl coupling reactions, it reacts with amines and alcohols to form amides and esters, respectively, which are essential structural motifs in many bioactive compounds.
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