3-Fluoro-4-hydroxyphenylacetic acid
98%
Reagent
Code: #187879
CAS Number
458-09-3
science Other reagents with same CAS 458-09-3
blur_circular Chemical Specifications
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Molecular Information
Weight
170.14 g/mol
Formula
C₈H₇FO₃
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Registry Numbers
MDL Number
MFCD00004348
thermostat
Physical Properties
Melting Point
132-134°C
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used in the synthesis of pharmaceutical intermediates, particularly in the development of fluorinated drug compounds where the fluorine atom enhances metabolic stability and bioavailability. Its hydroxy and acetic acid functional groups allow for easy derivatization, making it valuable in constructing active pharmaceutical ingredients (APIs) for central nervous system agents and anti-inflammatory drugs. Commonly employed in coupling reactions to form esters, amides, or glycosides in medicinal chemistry. Also utilized in the preparation of radiolabeled compounds for positron emission tomography (PET) imaging due to the presence of fluorine-18 isotope compatibility.