4-Fluoro-2-(trifluoromethyl)benzenesulfonyl Chloride
≥98%(GC)
Reagent
Code: #187942
CAS Number
176225-09-5
science Other reagents with same CAS 176225-09-5
blur_circular Chemical Specifications
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Molecular Information
Weight
262.60 g/mol
Formula
C₇H₃ClF₄O₂S
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Registry Numbers
MDL Number
MFCD01091000
thermostat
Physical Properties
Melting Point
50°C
Boiling Point
76°C|0.07kPa
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Storage & Handling
Storage
2-8°C, dry, inert gas storage
description Product Description
Used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the production of sulfa-based active ingredients. Its electrophilic sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester linkages. Commonly employed in the development of herbicides and fungicides due to the enhanced lipophilicity and metabolic stability imparted by the fluorinated aromatic ring. Also utilized in medicinal chemistry for modifying bioactive molecules to improve their pharmacokinetic properties.
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