4-Fluoro-2-(trifluoromethyl)benzenesulfonyl Chloride

≥98%(GC)

Reagent Code: #187942
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CAS Number 176225-09-5

science Other reagents with same CAS 176225-09-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 262.60 g/mol
Formula C₇H₃ClF₄O₂S
badge Registry Numbers
MDL Number MFCD01091000
thermostat Physical Properties
Melting Point 50°C
Boiling Point 76°C|0.07kPa
inventory_2 Storage & Handling
Storage 2-8°C, dry, inert gas storage

description Product Description

Used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the production of sulfa-based active ingredients. Its electrophilic sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester linkages. Commonly employed in the development of herbicides and fungicides due to the enhanced lipophilicity and metabolic stability imparted by the fluorinated aromatic ring. Also utilized in medicinal chemistry for modifying bioactive molecules to improve their pharmacokinetic properties.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿640.00
inventory 5g
10-20 days ฿2,160.00
inventory 10g
10-20 days ฿4,270.00
inventory 25g
10-20 days ฿9,270.00
inventory 100g
10-20 days ฿27,090.00
4-Fluoro-2-(trifluoromethyl)benzenesulfonyl Chloride
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Used as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the production of sulfa-based active ingredients. Its electrophilic sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester linkages. Commonly employed in the development of herbicides and fungicides due to the enhanced lipophilicity and metabolic stability imparted by the fluorinated aromatic ring. Also utilized in medicinal chemistry for modifying bioactive molecules to improve their pharmacokinetic properties.
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