4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
98%
Reagent
Code: #188062
CAS Number
779331-49-6
science Other reagents with same CAS 779331-49-6
blur_circular Chemical Specifications
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Molecular Information
Weight
238.06 g/mol
Formula
C₁₂H₁₆BFO₃
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Registry Numbers
MDL Number
MFCD16994352
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Physical Properties
Boiling Point
333.3±32.0℃ at 760 mmHg
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Storage & Handling
Density
1.15±0.1 g/cm3
Storage
2-8℃, sealed, dried
description Product Description
Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates mild and selective coupling with aryl halides, making it valuable in the development of complex organic molecules, including bioactive compounds and functional materials. The presence of a phenolic hydroxyl group allows for further derivatization, enhancing its utility in multi-step synthetic routes. Commonly employed in the preparation of fluorinated aromatic compounds, which are important in drug discovery due to their improved metabolic stability and binding affinity.
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