4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol

98%

Reagent Code: #188062
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CAS Number 779331-49-6

science Other reagents with same CAS 779331-49-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 238.06 g/mol
Formula C₁₂H₁₆BFO₃
badge Registry Numbers
MDL Number MFCD16994352
thermostat Physical Properties
Boiling Point 333.3±32.0℃ at 760 mmHg
inventory_2 Storage & Handling
Density 1.15±0.1 g/cm3
Storage 2-8℃, sealed, dried

description Product Description

Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates mild and selective coupling with aryl halides, making it valuable in the development of complex organic molecules, including bioactive compounds and functional materials. The presence of a phenolic hydroxyl group allows for further derivatization, enhancing its utility in multi-step synthetic routes. Commonly employed in the preparation of fluorinated aromatic compounds, which are important in drug discovery due to their improved metabolic stability and binding affinity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿1,020.00
inventory 5g
10-20 days ฿5,020.00
inventory 50g
10-20 days ฿30,510.00
4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol
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Used primarily as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates mild and selective coupling with aryl halides, making it valuable in the development of complex organic molecules, including bioactive compounds and functional materials. The presence of a phenolic hydroxyl group allows for further derivatization, enhancing its utility in multi-step synthetic routes. Commonly employed in the preparation of fluorinated aromatic compounds, which are important in drug discovery due to their improved metabolic stability and binding affinity.
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