3-Fluoro-4-(trifluoromethyl)pyridin-2(1H)-one
99%
Reagent
Code: #188076
CAS Number
1227594-89-9
science Other reagents with same CAS 1227594-89-9
blur_circular Chemical Specifications
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Molecular Information
Weight
181.0877328 g/mol
Formula
C₆H₃F₄NO
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Registry Numbers
MDL Number
MFCD26405803
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Physical Properties
Boiling Point
189.6±40.0℃ at 760 mmHg
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Storage & Handling
Density
1.48±0.1 g/cm3
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its fluorinated structure enhances binding affinity and metabolic stability in drug candidates. Also employed in agrochemicals to improve the efficacy of herbicides and pesticides due to its electron-withdrawing properties and resistance to degradation. Commonly utilized in medicinal chemistry for structure-activity relationship (SAR) studies involving fluorinated heterocycles.
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