2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

97%

Reagent Code: #188097
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CAS Number 870238-67-8

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blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 247.07 g/mol
Formula C₁₃H₁₅BFNO₂
badge Registry Numbers
MDL Number MFCD16996321
thermostat Physical Properties
Boiling Point 346.6±32.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, dry seal

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the preparation of fluorinated aromatic compounds. The presence of the nitrile and fluorine groups enhances reactivity and allows further functionalization, making it valuable in the development of active pharmaceutical ingredients (APIs) and complex organic molecules. Commonly applied in medicinal chemistry for constructing biaryl structures with improved metabolic stability and binding affinity.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿1,990.00
inventory 25g
10-20 days ฿4,690.00
2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the preparation of fluorinated aromatic compounds. The presence of the nitrile and fluorine groups enhances reactivity and allows further functionalization, making it valuable in the development of active pharmaceutical ingredients (APIs) and complex organic molecules. Commonly applied in medicinal chemistry for constructing biaryl structures with improved metabolic stability and binding affinity.
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