2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
97%
Reagent
Code: #188097
CAS Number
870238-67-8
science Other reagents with same CAS 870238-67-8
blur_circular Chemical Specifications
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Molecular Information
Weight
247.07 g/mol
Formula
C₁₃H₁₅BFNO₂
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Registry Numbers
MDL Number
MFCD16996321
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Physical Properties
Boiling Point
346.6±32.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry seal
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions for the synthesis of pharmaceuticals and agrochemicals. Its boronate ester group enables efficient carbon-carbon bond formation, particularly in the preparation of fluorinated aromatic compounds. The presence of the nitrile and fluorine groups enhances reactivity and allows further functionalization, making it valuable in the development of active pharmaceutical ingredients (APIs) and complex organic molecules. Commonly applied in medicinal chemistry for constructing biaryl structures with improved metabolic stability and binding affinity.
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