5-Fluoro-2-methylpyrimidin-4-amine
≥95%
Reagent
Code: #188126
CAS Number
1416372-67-2
science Other reagents with same CAS 1416372-67-2
blur_circular Chemical Specifications
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Molecular Information
Weight
127.12 g/mol
Formula
C₅H₆FN₃
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Registry Numbers
MDL Number
MFCD23099431
thermostat
Physical Properties
Boiling Point
209.2±20.0°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in the preparation of active pharmaceutical ingredients (APIs) targeting tyrosine kinases and other signaling proteins involved in tumor growth. Its fluorinated pyrimidine structure enhances binding affinity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity. Also utilized in agrochemical research for designing novel pesticides with improved efficacy.