(6-Fluoropyridin-2-yl)boronic acid
≥95%
Reagent
Code: #188137
CAS Number
916176-61-9
science Other reagents with same CAS 916176-61-9
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Molecular Information
Weight
140.91 g/mol
Formula
C₅H₅BFNO₂
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Registry Numbers
MDL Number
MFCD08705713
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Storage & Handling
Storage
-20°C, stored in inert gas
description Product Description
Used as a key intermediate in pharmaceutical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct fluorinated pyridine derivatives. These compounds are valuable in the development of agrochemicals, medicinal agents, and functional materials due to the enhanced metabolic stability and bioavailability imparted by the fluoropyridine moiety. Its boronic acid group enables efficient carbon-carbon bond formation under mild conditions, making it suitable for late-stage functionalization in drug discovery. Commonly employed in the preparation of kinase inhibitors and other biologically active molecules where fluorine substitution improves target binding and pharmacokinetic properties.
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