1-(2-Fluoro-4-nitrophenyl)piperazine
98%
Reagent
Code: #188730
CAS Number
154590-33-7
science Other reagents with same CAS 154590-33-7
blur_circular Chemical Specifications
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Molecular Information
Weight
225.22 g/mol
Formula
C₁₀H₁₂FN₃O₂
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Registry Numbers
MDL Number
MFCD01572463
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Physical Properties
Melting Point
70-73 °C
Boiling Point
392.728 °C at 760 mmHg
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Storage & Handling
Storage
Room temperature, dry, light-proof
description Product Description
Used primarily as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of active pharmaceutical ingredients (APIs) for central nervous system (CNS) agents. It serves as a building block in the preparation of selective receptor modulators, including serotonin and dopamine receptor ligands. Its structure facilitates the creation of more complex molecules with potential antipsychotic, antidepressant, or anxiolytic activity. Commonly employed in medicinal chemistry research for structure-activity relationship (SAR) studies due to the presence of both electron-withdrawing nitro and fluorine groups, which influence binding affinity and metabolic stability. Also utilized in the preparation of fluorescent probes and labeled compounds for biochemical assays.
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