2',3'-cGAMP sodium salt
98%
Reagent
Code: #190860
Alias
Related CAS: 1441190-66-4
CAS Number
2734858-36-5
science Other reagents with same CAS 2734858-36-5
blur_circular Chemical Specifications
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Molecular Information
Weight
718.4 g/mol
Formula
C₂₀H₂₂N₁₀Na₂O₁₃P₂
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Storage & Handling
Storage
-20°C, sealed, dry
description Product Description
Used as a potent immune stimulator in research and therapeutic development, particularly in cancer immunotherapy. It activates the STING (stimulator of interferon genes) pathway, triggering robust type I interferon responses that enhance antitumor immunity. Employed in vaccine adjuvants to boost immune response against pathogens. Investigated for use in combination with checkpoint inhibitors to improve efficacy in cold tumors. Also utilized in cellular assays to study innate immune signaling and antiviral defense mechanisms. Its sodium salt form improves solubility and stability for in vitro and in vivo applications.
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