4,4,5,5-Tetramethyl-2-(4-((tetrahydro-2H-pyran-2-yl)methoxy)phenyl)-1,3,2-dioxaborolane

95%

Reagent Code: #192814
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CAS Number 2246378-88-9

science Other reagents with same CAS 2246378-88-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 318.22 g/mol
Formula C₁₈H₂₇BO₄
badge Registry Numbers
MDL Number MFCD31735826
thermostat Physical Properties
Boiling Point 432.7±20.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.07±0.1 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl halides under mild conditions, making it valuable in the preparation of complex organic molecules, particularly in drug discovery and development. The tetrahydropyranyl (THP) protecting group enhances stability and solubility during multi-step syntheses, allowing selective deprotection when needed. Commonly employed in the construction of biaryl systems found in bioactive compounds.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿2,630.00
inventory 250mg
10-20 days ฿4,450.00

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4,4,5,5-Tetramethyl-2-(4-((tetrahydro-2H-pyran-2-yl)methoxy)phenyl)-1,3,2-dioxaborolane
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Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl halides under mild conditions, making it valuable in the preparation of complex organic molecules, particularly in drug discovery and development. The tetrahydropyranyl (THP) protecting group enhances stability and solubility during multi-step syntheses, allowing selective deprotection when needed. Commonly employed in the construction of biaryl systems found in bioactive compounds.
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