5-Bromo-3,3-dimethyl-isoindolin-1-one
95%
Reagent
Code: #192832
CAS Number
959756-18-4
science Other reagents with same CAS 959756-18-4
blur_circular Chemical Specifications
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Molecular Information
Weight
240.1 g/mol
Formula
C₁₀H₁₀BrNO
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Registry Numbers
MDL Number
MFCD27937924
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Physical Properties
Boiling Point
412.3±45.0 °C(Predicted)
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Storage & Handling
Density
1.449±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors for cancer treatment. Its bromo functional group allows for easy coupling reactions, such as Suzuki or Buchwald-Hartwig, enabling the construction of complex bioactive molecules. Commonly employed in medicinal chemistry for lead optimization due to its stable isoindolinone core and favorable pharmacokinetic properties. Also utilized in research settings to design CNS-active compounds owing to its ability to cross the blood-brain barrier.
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