2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole hydrate
95%
Reagent
Code: #192998
CAS Number
1288338-69-1
science Other reagents with same CAS 1288338-69-1
blur_circular Chemical Specifications
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Molecular Information
Weight
371.38 g/mol
Formula
C₁₆H₁₆F₃N₃O₂S
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Storage & Handling
Storage
-20°C, Sealed, Dry
description Product Description
Used as a key intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of tenatoprazole and related anti-ulcer agents. Its structure supports the inhibition of gastric acid secretion by targeting the H+/K+-ATPase enzyme in the stomach lining. Due to the presence of trifluoroethoxy and benzimidazole moieties, it exhibits enhanced metabolic stability and binding affinity, making it valuable in developing long-acting PPIs for treating gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The hydrate form improves handling and solubility during pharmaceutical processing.
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