2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole hydrate

95%

Reagent Code: #192998
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CAS Number 1288338-69-1

science Other reagents with same CAS 1288338-69-1

blur_circular Chemical Specifications

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Weight 371.38 g/mol
Formula C₁₆H₁₆F₃N₃O₂S
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used as a key intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of tenatoprazole and related anti-ulcer agents. Its structure supports the inhibition of gastric acid secretion by targeting the H+/K+-ATPase enzyme in the stomach lining. Due to the presence of trifluoroethoxy and benzimidazole moieties, it exhibits enhanced metabolic stability and binding affinity, making it valuable in developing long-acting PPIs for treating gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The hydrate form improves handling and solubility during pharmaceutical processing.

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Size Availability Unit Price Quantity
inventory 25g
10-20 days ฿1,610.00
inventory 500g
10-20 days ฿18,530.00
inventory 100g
10-20 days ฿5,290.00

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2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole hydrate
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Used as a key intermediate in the synthesis of proton pump inhibitors (PPIs), particularly in the production of tenatoprazole and related anti-ulcer agents. Its structure supports the inhibition of gastric acid secretion by targeting the H+/K+-ATPase enzyme in the stomach lining. Due to the presence of trifluoroethoxy and benzimidazole moieties, it exhibits enhanced metabolic stability and binding affinity, making it valuable in developing long-acting PPIs for treating gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. The hydrate form improves handling and solubility during pharmaceutical processing.
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