tert-butyl 2-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)amino)acetate
95%
Reagent
Code: #193040
CAS Number
2229976-11-6
science Other reagents with same CAS 2229976-11-6
blur_circular Chemical Specifications
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Molecular Information
Weight
373.4 g/mol
Formula
C₁₉H₂₃N₃O₅
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Storage & Handling
Storage
Room temperature
description Product Description
Used as an intermediate in the synthesis of biologically active compounds, particularly in the development of targeted protein degradation therapeutics. It serves as a key building block in the preparation of cereblon E3 ligase modulators, which are important in oncology research. Its structure enables conjugation to other pharmacophores for the design of PROTACs (proteolysis-targeting chimeras), facilitating selective degradation of disease-related proteins. Commonly employed in medicinal chemistry for optimizing drug candidates with improved stability and binding affinity.
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