4-Hydroxy-3-(trifluoromethyl)benzaldehyde
98%
Reagent
Code: #193784
CAS Number
220227-98-5
science Other reagents with same CAS 220227-98-5
blur_circular Chemical Specifications
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Molecular Information
Weight
190.12 g/mol
Formula
C₈H₅F₃O₂
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Registry Numbers
MDL Number
MFCD01091006
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Physical Properties
Melting Point
159-163°C
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the production of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its structure supports the formation of bioactive molecules due to the presence of both aldehyde and hydroxyl functional groups, which allow for further chemical modifications. Commonly employed in the development of fluorinated organic compounds, where the trifluoromethyl group enhances metabolic stability and lipophilicity. Also utilized in agrochemicals for creating herbicides and fungicides, benefiting from the electron-withdrawing properties of the trifluoromethyl group that improve environmental stability. Serves as a building block in liquid crystal materials and organic semiconductors due to its rigid aromatic framework and polar substituents.
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