4-(3-Iodo-1H-pyrazol-4-yl)-2-(methylthio)pyrimidine
95%
Reagent
Code: #200305
CAS Number
1111638-74-4
science Other reagents with same CAS 1111638-74-4
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
318.14 g/mol
Formula
C₈H₇IN₄S
badge
Registry Numbers
MDL Number
MFCD12756165
thermostat
Physical Properties
Boiling Point
435.2°Cat760mmHg
inventory_2
Storage & Handling
Storage
2-8°C, protected from light, stored in inert gas
description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in pharmaceutical research targeting cancer therapies. Its structure allows for selective binding to enzyme active sites, making it valuable in developing drugs that modulate cellular signaling pathways. Commonly employed in the preparation of small-molecule inhibitors targeting BTK (Bruton's tyrosine kinase) and other tyrosine kinases involved in immune response and tumor growth. Also utilized in radiolabeling studies due to the presence of iodine, enabling imaging and tracer applications in preclinical research.