Used as a key intermediate in pharmaceutical synthesis, particularly in the development of protease inhibitors and other bioactive molecules. Its rigid bicyclic structure enhances stereoselectivity in reactions, making it valuable in asymmetric synthesis. The iodine substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Heck couplings, enabling the construction of complex organic frameworks. Also employed in the preparation of enzyme inhibitors due to its ability to mimic transition states in metabolic pathways.