JNJ-10229571

10mM in DMSO

Reagent Code: #201286
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CAS Number 524923-88-4

science Other reagents with same CAS 524923-88-4

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scatter_plot Molecular Information
Weight 389.47 g/mol
Formula C₂₂H₁₉N₃O₂S
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research for the treatment of autoimmune and inflammatory diseases, particularly psoriasis and atopic dermatitis. It functions as a selective inhibitor of tyrosine kinase 2 (TYK2), a key enzyme in the JAK-STAT signaling pathway involved in immune responses. By modulating this pathway, it helps reduce the production of pro-inflammatory cytokines without broadly suppressing the immune system. Its targeted mechanism offers potential for improved safety compared to pan-JAK inhibitors. Currently under investigation in clinical trials to evaluate efficacy, dosing, and long-term safety in chronic inflammatory conditions.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿7,060.00
JNJ-10229571
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Used in research for the treatment of autoimmune and inflammatory diseases, particularly psoriasis and atopic dermatitis. It functions as a selective inhibitor of tyrosine kinase 2 (TYK2), a key enzyme in the JAK-STAT signaling pathway involved in immune responses. By modulating this pathway, it helps reduce the production of pro-inflammatory cytokines without broadly suppressing the immune system. Its targeted mechanism offers potential for improved safety compared to pan-JAK inhibitors. Currently under investigation in clinical trials to evaluate efficacy, dosing, and long-term safety in chronic inflammatory conditions.
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