JNJ-10229571
10mM in DMSO
Reagent
Code: #201286
CAS Number
524923-88-4
science Other reagents with same CAS 524923-88-4
blur_circular Chemical Specifications
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Molecular Information
Weight
389.47 g/mol
Formula
C₂₂H₁₉N₃O₂S
inventory_2
Storage & Handling
Storage
-20°C
description Product Description
Used in research for the treatment of autoimmune and inflammatory diseases, particularly psoriasis and atopic dermatitis. It functions as a selective inhibitor of tyrosine kinase 2 (TYK2), a key enzyme in the JAK-STAT signaling pathway involved in immune responses. By modulating this pathway, it helps reduce the production of pro-inflammatory cytokines without broadly suppressing the immune system. Its targeted mechanism offers potential for improved safety compared to pan-JAK inhibitors. Currently under investigation in clinical trials to evaluate efficacy, dosing, and long-term safety in chronic inflammatory conditions.