Used in research as a selective agonist for the GPR132 receptor, JKC 363 TFA helps investigate signaling pathways involved in immune cell regulation and inflammatory responses. It is primarily applied in cellular and molecular studies to explore macrophage activation and its role in diseases such as atherosclerosis and cancer. Due to its stability and specificity, it is suitable for in vitro assays and animal models aimed at understanding G protein-coupled receptor function.