L-Glutamine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-phenyl-
98%
Reagent
Code: #201637
CAS Number
198134-12-2
science Other reagents with same CAS 198134-12-2
blur_circular Chemical Specifications
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Molecular Information
Weight
444.4792 g/mol
Formula
C₂₆H₂₄N₂O₅
thermostat
Physical Properties
Boiling Point
753.4±60.0 °C(Predicted)
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Storage & Handling
Density
1.320±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used primarily as a protected amino acid building block in solid-phase peptide synthesis (SPPS), this compound enables selective and efficient incorporation of glutamine residues into peptide chains. The fluorenylmethyloxycarbonyl (Fmoc) group protects the alpha-amino function, allowing for mild base-induced deprotection under piperidine treatment, while the N-phenyl group stabilizes the side chain amide. Its main application lies in the synthesis of complex peptides and proteins in research and pharmaceutical development, particularly where glutamine side-chain reactivity needs to be controlled. It is compatible with resin-bound synthesis and widely used in automated peptide synthesizers.
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