LDN-193189 2HCl

10mM in Water

Reagent Code: #201756
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CAS Number 1435934-00-1

science Other reagents with same CAS 1435934-00-1

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Weight 479.4 g/mol
Formula C₂₅H₂₄Cl₂N₆
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in research settings, this compound acts as a potent inhibitor of the BMP (bone morphogenetic protein) signaling pathway by targeting ALK2 and ALK3 receptors. It is widely applied in stem cell studies to direct cell differentiation, particularly in promoting neural induction and suppressing mesodermal development in pluripotent stem cells. Researchers also utilize it in regenerative medicine and disease modeling, including studies related to fibrodysplasia ossificans progressiva (FOP), a rare disorder involving abnormal bone formation in soft tissues. Its ability to modulate BMP signaling makes it valuable in investigating embryonic development, tissue engineering, and potential therapeutic strategies for bone-related disorders.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿6,800.00
LDN-193189 2HCl
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Used primarily in research settings, this compound acts as a potent inhibitor of the BMP (bone morphogenetic protein) signaling pathway by targeting ALK2 and ALK3 receptors. It is widely applied in stem cell studies to direct cell differentiation, particularly in promoting neural induction and suppressing mesodermal development in pluripotent stem cells. Researchers also utilize it in regenerative medicine and disease modeling, including studies related to fibrodysplasia ossificans progressiva (FOP), a rare disorder involving abnormal bone formation in soft tissues. Its ability to modulate BMP signaling makes it valuable in investigating embryonic development, tissue engineering, and potential therapeutic strategies for bone-related disorders.
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