LDN-193189 2HCl
10mM in Water
Reagent
Code: #201756
CAS Number
1435934-00-1
science Other reagents with same CAS 1435934-00-1
blur_circular Chemical Specifications
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Molecular Information
Weight
479.4 g/mol
Formula
C₂₅H₂₄Cl₂N₆
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in research settings, this compound acts as a potent inhibitor of the BMP (bone morphogenetic protein) signaling pathway by targeting ALK2 and ALK3 receptors. It is widely applied in stem cell studies to direct cell differentiation, particularly in promoting neural induction and suppressing mesodermal development in pluripotent stem cells. Researchers also utilize it in regenerative medicine and disease modeling, including studies related to fibrodysplasia ossificans progressiva (FOP), a rare disorder involving abnormal bone formation in soft tissues. Its ability to modulate BMP signaling makes it valuable in investigating embryonic development, tissue engineering, and potential therapeutic strategies for bone-related disorders.
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