Licochalcone B is widely used in cosmetic and skincare formulations due to its strong antioxidant and anti-inflammatory properties. It helps protect the skin from oxidative stress caused by environmental pollutants and UV radiation, making it effective in anti-aging products. Its ability to inhibit melanin production also makes it useful in skin-brightening and hyperpigmentation treatments. Additionally, Licochalcone B exhibits antimicrobial activity, which supports its use in products designed for acne-prone or sensitive skin. In pharmaceutical research, it is studied for potential anticancer and antidiabetic effects due to its influence on cellular signaling pathways and glucose metabolism.