Lochnericine is primarily used in scientific research, particularly in the study of alkaloid toxicity and its effects on the nervous system. It serves as a reference compound in pharmacological investigations due to its structural similarity to other indole alkaloids with biological activity. Its presence in plants of the Apocynaceae family makes it relevant in ethnobotanical studies, especially in understanding the toxic components of medicinal plants. Due to its toxic properties, it is also examined in toxicology for risk assessment of plant-derived preparations. Currently, it has no approved medical or industrial applications.