Used in the synthesis of antibody-drug conjugates (ADCs) for targeted cancer therapy. The propargyl and amine functional groups enable site-specific conjugation through click chemistry or amide coupling, allowing precise attachment to monoclonal antibodies. This facilitates delivery of the cytotoxic payload selectively to tumor cells, improving therapeutic efficacy and reducing systemic toxicity. Commonly applied in the development of novel oncology therapeutics, particularly for hematological malignancies.