methyl 2-(chlorocarbonyl)benzoate
≥96.5% (HPLC); 96.5-103.5% (AT); 97%
Reagent
Code: #209779
CAS Number
4397-55-1
science Other reagents with same CAS 4397-55-1
blur_circular Chemical Specifications
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Molecular Information
Weight
198.60 g/mol
Formula
C₉H₇ClO₃
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Registry Numbers
MDL Number
MFCD11656039
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Storage & Handling
Storage
2-8°C, sealed, dry, inflatable
description Product Description
Methyl 2-(chlorocarbonyl)benzoate is a specialty chemical intermediate used in organic synthesis, particularly for pharmaceuticals, agrochemicals, and fine chemicals. As a bifunctional reagent featuring an acid chloride and an ortho-methyl ester group, it facilitates the introduction of the 2-(methoxycarbonyl)benzoyl moiety into molecules. It reacts with nucleophiles such as amines to form amides, enabling the construction of heterocyclic compounds and complex ring systems. Commonly applied in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), dyes, and other bioactive molecules, its ortho substitution allows for directed cyclization reactions and selective functional group transformations.