3-Methyl-6-(4-methyl-3-nitrophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-8-amine
97%
Reagent
Code: #211951
CAS Number
1956334-72-7
science Other reagents with same CAS 1956334-72-7
blur_circular Chemical Specifications
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Molecular Information
Weight
284.2734 g/mol
Formula
C₁₃H₁₂N₆O₂
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Registry Numbers
MDL Number
MFCD29921192
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Storage & Handling
Storage
2-8°C, drying away from light
description Product Description
Used primarily in research as a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), this compound is valuable in studying neurological disorders such as schizophrenia, Huntington's disease, and other psychiatric conditions involving dysregulation of the striatal pathway. Its ability to modulate intracellular cAMP and cGMP levels in the brain makes it a useful tool for investigating signal transduction mechanisms. Due to its high blood-brain barrier permeability and in vivo activity, it is employed in preclinical models to assess the therapeutic potential of PDE10A inhibition. Not intended for human use, it serves exclusively as a pharmacological probe in neuroscience research.