5-(Methyl-d3)-dibenzothiophenium, 1,1,1-trifluoromethanesulfonate
99.8 atom % D, CP:98%
Reagent
Code: #212019
CAS Number
2251781-83-4
science Other reagents with same CAS 2251781-83-4
blur_circular Chemical Specifications
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Molecular Information
Weight
351.38 g/mol
Formula
C₁₄H₈D₃F₃O₃S₂
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a deuterated reagent in organic synthesis, particularly in cross-coupling reactions where the deuterated methyl group serves as a stable isotope label. Its primary application lies in pharmaceutical research for tracing metabolic pathways and studying reaction mechanisms due to the kinetic isotope effect provided by the CD₃ group. The triflate anion enhances its utility in palladium-catalyzed reactions, enabling the introduction of deuterated aromatic sulfides into complex molecules. This compound is valuable in the development and analysis of deuterated drugs, where improved metabolic stability and altered pharmacokinetics are desired.